Taxonomic difference in marine bloom-forming phytoplanktonic species affects the dynamics of both bloom-responding prokaryotes and prokaryotic viruses

ABSTRACTThe production of dissolved organic matter during phytoplankton blooms and consumption by heterotrophic prokaryotes promote marine carbon biogeochemical cycling.Although prokaryotic viruses presumably affect this process, their dynamics during blooms are not fully understood.Here, we investigated the effects of taxonomic difference in bloom

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Fluconazole Failure in the Treatment of Coccidioidal Meningitis

Introduction: Coccidioidal meningitis (CM) is the most lethal form of disseminated coccidioidomycosis.Current guidelines recommend fluconazole as initial therapy but there has been a paucity of data regarding failure of fluconazole and optimal fluconazole dosage in the treatment of CM.We conducted this study to understand risk factors for fluconazo

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